Roivant acquires therapy to treat Chronic Cough in IPF patients

Roivant Sciences announced that it has completed a transaction with Patara Pharma to acquire global rights to PA101 (now called RVT-1601), a novel formulation of inhaled cromolyn sodium delivered through a proprietary nebulizer device designed to yield high lung deposition and distribution, as well as related assets owned by Patara Pharma.

In a completed Phase 2a trial, RVT-1601 demonstrated a statistically significant reduction in daytime and 24-hour cough frequency among idiopathic pulmonary fibrosis (IPF) patients versus placebo after 14 days of treatment. This reduction was supported by positive trends in cough-specific quality of life and cough severity, as assessed by patients in the study.

The therapy was well tolerated, with no significant treatment-related adverse events reported in clinical studies to date. Roivant plans to initiate a Phase 2b study to identify the optimal dose for RVT-1601.

“We are excited to expedite the development of this promising therapeutic,” said Mayukh Sukhatme, M.D., President of Roivant Pharma. “It will form the foundation for a new Vant at Roivant Pharma with an experienced leadership team focused on advancing innovative treatments for respiratory diseases with high unmet needs.”

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News Source: http://roivant.com/roivant-adds-investigational-therapeutic-for-the-treatment-of-chronic-cough-in-patients-with-idiopathic-pulmonary-fibrosis-to-pipeline/

Image Source: http://pulmonaryfibrosismd.com/pulmonary-fibrosis-exacerbation/