Non Motor symptoms for Parkinson’s more common in women as compared to men, study states

As per a recent study results published in BMJ open, Certain Non Motor symptoms for Parkinson’s are more common in women as compared with men. The study was aimed at determining the frequency of non-motor symptoms (NMS) in in male and female patients of Parkinson’s disease (PD) presenting to a movement disorder clinic at a tertiary care centre in Pakistan.

85 patients were included in the study and the Inclusion criteria was the patients with PD diagnosed according to the UK Parkinson’s Disease Society Brain Bank Clinical Diagnostic Criteria, age ≥18 years, able to give consent and have no difficulty in answering questions. Other diseases that resemble PD, stroke, dementia, and the patients unable to provide information and history of antipsychotic use were excluded from the study.

Results of the study:

The NMSQuest revealed a mean of nearly seven different NMS per patient. Autonomic problems such as constipation (56%) and nocturia (49%) were the most common NMS, while urinary urgency was reported by 35% of patients. Low mood and feeling sad were reported by 47%, whereas feeling anxious/panicky was reported by 36%. Problem with memory was reported by 45% of patients. Feeling of light-headedness and dizziness was reported by 40% of patients. Problems with sexual relationship were reported by 30% of patients. The most common sleep problem was difficulty in sleep (29%). Pain not related to the musculoskeletal system was reported by 30% of patients. Loss or change in the ability to taste or smell was reported by 29% of patients. The rest of NMS were less than 25% in frequency. Feeling sad or blue, feeling light-headed/dizzy, unexplained pain, unpleasant sensations in the legs, difficulty in swallowing and faecal incontinence were more common in female participants, while problems with sex were more common in male participants.

The study concluded that NMS are quite prevalent in PD in our population. Certain NMS are more common in women as compared with men. The study further highlighted that there is a need for a large-scale study to look for the association of different NMS with sex.

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News Source: http://bmjopen.bmj.com/content/8/5/e019172

Image Source: https://consumer.healthday.com/cognitive-health-information-26/parkinson-s-news-526/are-women-with-parkinson-s-at-a-disadvantage-729076.html